PHARMACOLOGY 1: • derivative of nipecotic acid and was "rationally designed" as an inhibitor of GABA uptake (as opposed to the discovery through random screenings)

blocks GABA reuptake in
forebrain by selective blockade
by GAT-1

ADJUNCTIVE TREATMENT OF
PARTIAL SEIZURES

Question

• derivative of nipecotic acid and  was "rationally designed" as an  inhibitor of GABA uptake (as  opposed to the discovery through random screenings)

blocks GABA reuptake in 
forebrain by selective blockade 
by GAT-1

ADJUNCTIVE TREATMENT OF 
PARTIAL SEIZURES

LEIGHTON DWIGHT OBILLOS · Accepted Answer

TIAGABINE
Gabitril®

PHARMACOLOGY 1

• derivative of nipecotic acid and was "rationally designed" as an inhibitor of GABA uptake (as opposed to the discovery through random screenings) blocks GABA reuptake in forebrain by selective blockade by GAT-1 ADJUNCTIVE TREATMENT OF PARTIAL SEIZURES

TIAGABINE Gabitril®

Author