• a substituted monosaccharide that is STUCTURALLY DIFFERENT from all other antiseizure drugs • blocks repetitive firing of cultured spinal cord neurons, involve blocking of VG Na+ channels • potentiates inhibitory effects of GABA • depresses the excitatory action of kainate on glutamate receptors • Effective against PARTIAL AND GENERALIZED TONIC-CLONIC SEIZURES • WEST'S SYNDROME, LENNOX-GASTAUT SYNDROME, ABSENCE SEIZURES • MIGRAINE