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molecular biology 1

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Question:

What's Prokaryotic mRNA Degradation involving multiple enzymes?

Author: Noura Al shalan



Answer:

Degradation of bacterial mRNAs is initiated by removal of a pyrophosphate from the 5′ terminus. Monophosphorylated mRNAs are degraded during translation in a two-step cycle involving endonucleolytic cleavages, followed by 3′ to 5′ digestion of the resulting fragments. 3′ polyadenylation can facilitate the degradation of mRNA fragments containing secondary structure.


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Degradation of bacterial mRNAs is initiated by removal of a pyrophosphate from the 5′ terminus.
Monophosphorylated mRNAs are degraded during translation in a two-step cycle involving endonucleolytic cleavages, followed by 3′ to 5′ digestion of the resulting fragments.
3′ polyadenylation can facilitate the degradation of mRNA fragments containing secondary structure.
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