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pharmacology chemotherapy

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Question:

Fluconazole uses

Author: Suzuki



Answer:

Fluconazole is employed prophylactically, with some success, for reducing fungal infections in recipients of bone marrow transplants. It inhibits the synthesis of fungal membrane ergosterol in the same manner as ketoconazole drug of choice for Cryptococcus neoformans after therapy with amphotericin B, for most candidemias, and for coccidioidomycosis. most forms of mucocutaneous candidiasis. Treatment failures due to resistance have been reported in some HIVinfected patients.] For the treatment of vaginal candidiasis, the dose is 150 mg as a single oral dose. Fluconazole is a drug of choice in esophageal and oropharyngeal candidiasis and for most infections caused by Coccidioides. A single oral dose usually eradicates vaginal candidiasis. Fluconazole is a drug of choice in esophageal and oropharyngeal candidiasis and for most infections caused by Coccidioides. The drug is also equivalent to amphotericin B in candidemia


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Suzuki
Suzuki