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MBS1002 Biomedical Approaches

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Question:

How does CRE recombinase work?

Author: Mirte Schattorie



Answer:

CRE recombinase is a tool to edit DNA. it recognises loxP sequences. when these sequences are in opposite directions, CRE reverses the gene sequence. when these loxP sequences are in the same direction, CRE cuts out one of the loxP sequences, and can thereby remove the gene in between the loxP sequences.


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