• Actions: Causes increased secretion, smooth muscle contraction (except vascular smooth muscle - relaxes), and changes in heart rate • CA: Postoperative nonobstructive urinary retention, neurogenic ileus and megacolon • S/E: Generalized cholinergic stimulation (sweating, salivation, flushing, decreased blood pressure, nausea, abdominal pain, diarrhea, bronchospasm)