MGD week 3: Explain the relationship between DNA damage and cancer

Question

Explain the relationship between DNA damage and cancer

B. Lee · Accepted Answer

Cancer 
- occurs when DNA repair fails 
6 hall marks 
- Self sufficiency in growth signals 
- insensitivity to anti-growth signals 
- avoids apoptosis 
- sustained angiogenesis 
- metastasis 
- tissue invasion

Leads to cancer

MGD week 3

Explain the relationship between DNA damage and cancer

Cancer - occurs when DNA repair fails 6 hall marks - Self sufficiency in growth signals - insensitivity to anti-growth signals - avoids apoptosis - sustained angiogenesis - metastasis - tissue invasion Leads to cancer

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