BBS2001 Threats and Defence Mechanisms: how do T cells migrate out of the lymph nodes?

Question

how do T cells migrate out of the lymph nodes?

Mirte Schattorie · Accepted Answer

naive T cell: following the gradient of SIP into the lymph fluid

effector T cell: SIP receptor is reexpressed after differentiation, T cells loose L-selectin and CCR7 expression and follow the gradient of SIP into the lymph fluid

BBS2001 Threats and Defence Mechanisms

How do T cells migrate out of the lymph nodes?

Naive T cell: following the gradient of SIP into the lymph fluid effector T cell: SIP receptor is reexpressed after differentiation, T cells loose L-selectin and CCR7 expression and follow the gradient of SIP into the lymph fluid

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