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From course:

BBS2001 Threats and Defence Mechanisms

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Question:

How do CD8 T cells work?

Author: Mirte Schattorie



Answer:

When it comes across an infected cell, it forms an immune synapse between itself and the target cell. through this synapse granules containing granzymes, perforin and other toxins are released. perforin makes little holes in the cell membrane of the target cell, which enables granzymes to enter. the serine protease of the granzymes then triggers the caspase cascade of the cell, inducing apoptosis


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