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Praxis exam study semester 2 --

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Question:

How does Disulfiram (Antabuse) work to help people remain absence from alcohol?

Author: Jade Ann Paterson



Answer:

Produces irreversible inhibition of aldehyde dehydrogenase (ALDH). Aldehyde dehydrogenase is the enzyme responsible for the oxidation of acetaldehyde (which is a metabolite of ethanol).


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