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From course:

BBS2001 Threats and Defence Mechanisms

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Question:

Why do penicillins work better on gram-positive than gram-negative bacteria?

Author: Mirte Schattorie



Answer:

The gram-negative bacteria have an outer membrane that the penicillins have to cross before they can do their job. this crossing depends on if the antibiotic fits through the pores of the bacteria. the gram-positive bacteria do not have this membrane


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