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molecular biology 1

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Question:

How is the Direction of Mismatch Repair Controlled?

Author: Noura Al shalan



Answer:

-There is a bias in the selection of which strand to replace at mismatches. -The strand lacking methylation at a hemimethylated GATCCTAG  is usually replaced. -The mismatch repair system is used to remove errors in a newly synthesized strand of DNA. At G-T and C-T mismatches, the T is preferentially removed.


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