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molecular biology 1

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Question:

What are Error-Prone Repair and Translesion Synthesis?

Author: Noura Al shalan



Answer:

-Damaged DNA that has not been repaired causes DNA polymerase III to stall during replication. -DNA polymerase V (coded by umuCD) or DNA polymerase IV (coded by dinB) can synthesize a complement to the damaged strand. -The DNA synthesized by repair DNA polymerases often has errors in its sequence (error-prone synthesis).


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-Damaged DNA that has not been repaired causes DNA polymerase III to stall during replication.
-DNA polymerase V (coded by umuCD) or DNA polymerase IV (coded by dinB) can synthesize a complement to the damaged strand.
-The DNA synthesized by repair DNA polymerases often has errors in its sequence (error-prone synthesis).
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