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molecular biology 1

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Question:

What does Creating the Replication Forks at the Origin oriC involve ?

Author: Noura Al shalan



Answer:

Six DnaC monomers bind each hexamer of DnaB, and this complex binds to the origin. • A hexamer of DnaB (a helicase) forms the replication fork. Gyrase and single-strand binding proteins (SSB) are also required. • A short region of A-T–rich DNA is melted. • DnaG primase is bound to the helicase complex and creates the replication forks.


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Six DnaC monomers bind each hexamer of DnaB, and this complex binds to the origin.
• A hexamer of DnaB (a helicase) forms the replication fork. Gyrase and single-strand binding proteins (SSB) are also required.
• A short region of A-T–rich DNA is melted.
• DnaG primase is bound to the helicase complex and creates the replication forks.
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