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level: Level 5

Questions and Answers List

level questions: Level 5

QuestionAnswer
Autoimmune Inflammatory Demyelinating Disease of the CNS. May consist of one or two acute neurologic episodes Can be Chronic, relapsing or progressive disease that may span 10 to 20 years.Multiple Sclerosis
Help DIMINISH the inflammatory responses that lead to demyelination of the axon sheaths. A/E: Depression, Local injection site reaction, Hepatic enzyme increases, Flu-like symptoms for MSInterferon B1a Interferon B1b
Synthetic polypeptide that RESEMBLES MYELIN PROTEIN Act as DECOY to T-cell attack. for MSGlatiramer
Oral DRUG ALTER LYMPHOCYTE MIGRATION, resulting in lower lymphocytes in the CNS Cause FIRST-DOSE BRADYCARDIA and associated with Increased RISK of INFECTION & MACULAR EDEMA for MSFingolimod
Oral pyrimidine Synthesis Inhibitor Leads to LOWER CONCENTRATION of ACTIVE LYMPHOCYTES in the CNS. May cause ELEVATED LIVER ENZYMES SHOULD BE AVOIDED IN PREGNANCY for MSTeriflunomide
Oral Agent ALTER CELLULAR RESPONSE to OXIDATIVE STRESS to reduce disease progression A/E: FLUSHING, ABDOMINAL PAIN for MSDimethyl Fumarate
MONOCLONAL ANTIBODY for patients who have FAILED FIRST-LINE THERAPIES for MSNatalizumab
Cytotoxic ANTHRACYCLINE ANALOG Kills T-cells for MSMitoxantrone
ORAL POTASSIUM CHANNEL BLOCKER IMPROVES WALKING SPEEDS in patients with MS symptomatic treatmentDalfampridine
The ONLY drug indicated for ALS (Amyotrophic Lateral Sclerosis) NMDA receptor antagonist Inhibits glutamate release and blocks sodium channels IMPROVE SURVIVAL TIME and delay the need for bentilator supportRiluzole