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Nervous system


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The functions of the nervous system
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Collect sensory input Motor output major controlling regulating and communicating system of the body Fast acting and chemical and electrical signals Center of all mental activity including thought learning and memory Keeps us in touch with our environment external and internal

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The functions of the nervous system
Collect sensory input Motor output major controlling regulating and communicating system of the body Fast acting and chemical and electrical signals Center of all mental activity including thought learning and memory Keeps us in touch with our environment external and internal
Collect sensory input
Sensory receptors means to obtain information about internal and external changes Integration of input Interpretation of sensory input to determine response to it
Motor output
Activation of effector organs (muscles and glands) produce is a response
Central nervous system (CNS)
1. Brain 2. Spinal cord Integration and command center
Peripheral nervous system (PNS)
1. Paired spinal nerves attached a spinal cord 2. Paired cranial nerves attached to brain Carry messages to and from the CNS Multiple divisions
PNS functional divisions
Sensory (afferent) division Motor (efferent) division
Sensory division (afferent)
Somatic afferent fibers -convey impulses from skin, skeletal muscles, and joints Visceral afferent fibers -Convey impulses from visceral organs
Motor division (efferent)
Transmits impulses from CNS to effector organs
Motor divisions of PNS
Somatic nervous system (voluntary) Autonomic nervous system (involuntary)
Somatic nervous system (voluntary)
Conscious control of skeletal muscle
Autonomic nervous system (Involuntary)
Visceral motor nerve fibers Regulate smooth muscle, cardiac muscles and glands To functional subdivisions: -Sympathetic (fight or flight) -Parasympathetic (Rest and digest)
Histology of nervous tissue
Very tightly packed cells To principal cell types: -Neurons -Neuroglia (glial cells)
Neurons
Excitable cells that transmit electrical signals
Neuroglia
Smaller supporting cells with various functions
Cells of the CNS
Astrocytes Microglia Ependymal cells Oligodendrocytes
Cells of the PNS
Satellite cells Schwann cells
Neurons special characteristics
Long lived (100 years or more) Amitotic High metabolic rate (requires continuous supply of oxygen and glucose) Plasma membrane functions in: -electrical signaling -Cell to cell interactions during development
Cell body (soma)
-Biosynthetic center of neurons with nucleus and organelles -well developed Golgi apparatus -rough ER called nissi bodies -network of neurofibrils -axon hillock: call shaped area with axon arises (determining place) -clusters of cell bodies nuclei and ganglia
Dendrites
-Short, tapering and diffusely branched -receptive region of neuron -Convey electrical signals (graded potentials) toward cell body
Axon
-One axon per cell arising from axon hillock -Long axons (nerve fibers) -conducting region: generate and transmit nerve impulses (action potentials) away from soma
Axon collaterals
Occasional branches
Telodendria
Numerous terminal branches
Synaptic knobs/Boutons/Axon terminals
Secretary region of neuron Release neurotransmitters to excite or inhibit other cells
Anterograde
Toward axon terminal
Retrograde
Toward the cell body
Astrocytes
-Most abundant, versatile, and highly branched glial cells -Cling to neurons, synaptic endings, and capillaries Functions: -Support and brace neurons -Help determine capillary permeability -Guide migration of young neurons -Control the chemical environment -Participate in information processing in the brain
Microglia
-Small, Ovid cells with thorny processes -Migrate toward injured neurons -Phagocytize microorganisms and neuronal debris -defensive cells in CNS Halloween cells eat up debris
Ependymal cells
-Range in shape from squamous to columnar -May be ciliated -Line the central cavities of the brain and spinal column -Separate the CNS interstitial fluid from the cerebrospinal fluid in the cavities
Oligodendrocytes
-Branched cells -Processes wrap CNS nerve fibers, forming insulating myelin sheaths
Satellite cells
Surround and support neuron cell bodies in PNS
Schwann cells
-Surround peripheral nerve fibers and form myelin sheaths -Vital to regeneration of damage peripheral nerve fibers
Myelin sheath
-Segmented protein lipoid sheath around most long or large diameter axons Functions to: -Protect an electrically insulate the axon -Increase speed of nerve impulse transmission
Myelin sheaths in PNS
-Schwann cells rap many times around the axon -Myelin sheath- Concentric layers of Schwann cell membrane -Neurilemma-Peripheral bulge of Schwann cell cytoplasm
Nodes of Ranvier
-Myelin sheath gaps between adjacent Schwann cells -Sites were axon collaterals can emerge
Unmyelinated axons
-Thin nerve fibers unmyelinated -One Schwann cell may incompletely enclosed 15 or more unmyelinated axons
Myelin sheaths in CNS
-Form by processes of oligodendrocytes not the whole cells -Nodes of Ranvier are present -No neurilemma -thinnest fibers are unmyelinated
White matter
Dense collections of myelinated fibers
Gray matter
Mostly neuron cell bodies and unmyelinated fibers
Functional classification of neurons
Sensory Motor Interneurons
Sensory (afferent)
Transmits impulses from sensory Receptors towards CNS
Motor (efferent)
Carry impulses from CNS to effectors
Interneurons (Association neurons)
Shuttle signals through CNS pathways most entirely within CNS
Structural classification of neurons
Multipolar Bipolar Unipolar
Multipolar
One axon and several dendrites Most abundant Motor neurons and interneurons
Bipolar
One axon and one dendrite
Unipolar
Single, short process that has two branches Peripheral process- More distal branch, often associated with a sensory receptor Central process- branch Entering the CNS