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level: Sedatives and anxiolytics

Questions and Answers List

level questions: Sedatives and anxiolytics

QuestionAnswer
How does clonidine release workAlpha 2 agonist- reduces NA release
How does buspirone work-5HT agonist
How does promethazine workAnti histamine leads to drowsiness stimulates presynaptic receptors on excitatory NT
Barbituates and bromides have been replaces byBenzos as safer- but still has issues with tolerance, dependance and withdrawal
Most common benzo currentlyAlprazalam
triazolam used forJet lag
Quazepam used forInsomnia
Main anxiolyticSSRI- first choice of drug
Buspirone used inGeneralised anxiety but less useful in panic and fear disorders
Pregabalin is aNon Bz anxiolytic
what are hypnoticsSleep drugs
BDz use in dentistryCombined with propofol for GA as muscle relaxant effect, also used as a premedication for dentistry
Epileptic seizures drug choice isMidazolam